Which level of protection would require both high respiratory and chemical skin protection?

The correct choice emphasizes the need for both high levels of respiratory protection and chemical skin protection, which is characteristic of Level A PPE. This level is utilized when there is a potential for exposure to hazardous substances that pose a significant threat and when the substances are not identifiable.

Level A protection typically includes a fully encapsulated suit that provides complete protection against hazardous materials. This is essential in scenarios where there is no known safe value for the type of exposure present or when dealing with highly toxic agents. The use of high-level respiratory protection is critical in such circumstances since it helps prevent inhalation hazards, while the chemical-resistant suit shields the skin from harmful contact with corrosive or permeating chemicals.

In contrast, other levels of protection, such as Level B, may provide high respiratory protection but do not require a fully encapsulated suit. Level C is used when contaminants are known and require less protective equipment, and Level D is for minimal hazard situations where no special protection is necessary. Therefore, Level A is the only option that fully encompasses both high respiratory and chemical skin protection needs.